Table 4.
Anti-inflammatory potentials of S. edelbergii extracts.
Paw Volume Changes (Mean ± SEM) | ||||||
---|---|---|---|---|---|---|
Treatment | Dose (mg/kg) | 1 h | 2 h | 3 h | Average Reading | % Inhibition |
Carrageenan | 1 mL | 1.07 ± 0.03 | 1.31 ± 0.01 | 1.63 ± 0.02 | 1.33 ± 0.02 | |
Diclofenac | 50 | 0.51 ± 0.02 | 0.35 ± 0.05 | 0.19 ± 0.03 | 0.35 ± 0.05 | 74 |
SECR | 50 | 0.91 ± 0.07 | 0.82 ± 0.01 | 0.69 ± 0.05 | 0.80 ± 0.04 * | 39 |
100 | 0.79 ± 0.04 | 0.66 ± 0.02 | 0.53 ± 0.06 | 0.66 ± 0.04 * | 50 | |
SEEA | 50 | 0.82 ± 0.06 | 0.73 ± 0.03 | 0.60 ± 0.01 | 0.71 ± 0.03 * | 47 |
100 | 0.74 ± 0.03 | 0.61 ± 0.02 | 0.49 ± 0.03 | 0.61 ± 0.02 * | 54 | |
SECH | 50 | 0.88 ± 0.05 | 0.79 ± 0.02 | 0.65 ± 0.04 | 0.77 ± 0.03 * | 42 |
100 | 0.79 ± 0.02 | 0.68 ± 0.04 | 0.56 ± 0.01 | 0.67 ± 0.02 * | 50 | |
SENB | 50 | 0.89 ± 0.03 | 0.78 ± 0.05 | 0.70 ± 0.02 | 0.79 ± 0.03 * | 41 |
100 | 0.81 ± 0.04 | 0.70 ± 0.02 | 0.62 ± 0.01 | 0.71 ± 0.02 * | 47 | |
SENH | 50 | 0.93 ± 0.01 | 0.83 ± 0.06 | 0.74 ± 0.03 | 0.83 ± 0.03 * | 38 |
100 | 0.86 ± 0.03 | 0.77 ± 0.03 | 0.68 ± 0.02 | 0.77 ± 0.03 * | 42 | |
SEAQ | 50 | 0.95 ± 0.02 | 0.87 ± 0.02 | 0.79 ± 0.03 | 0.87 ± 0.02 * | 35 |
100 | 0.88 ± 0.03 | 0.81 ± 0.02 | 0.75 ± 0.01 | 0.81 ± 0.02 * | 39 |
SE, S. edelbergii; NH, n-hexane; AQ, aqueous; CH, chloroform; NB, n-BuOH; EA, EtOAc; CR, crude. Diclofenac sodium is the positive control. n = 3 with p ≤ 0.05 *; data were taken as mean ± SEM.