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. 2021 Jun 19;26(12):3740. doi: 10.3390/molecules26123740

Table 4.

Anti-inflammatory potentials of S. edelbergii extracts.

Paw Volume Changes (Mean ± SEM)
Treatment Dose (mg/kg) 1 h 2 h 3 h Average Reading % Inhibition
Carrageenan 1 mL 1.07 ± 0.03 1.31 ± 0.01 1.63 ± 0.02 1.33 ± 0.02
Diclofenac 50 0.51 ± 0.02 0.35 ± 0.05 0.19 ± 0.03 0.35 ± 0.05 74
SECR 50 0.91 ± 0.07 0.82 ± 0.01 0.69 ± 0.05 0.80 ± 0.04 * 39
100 0.79 ± 0.04 0.66 ± 0.02 0.53 ± 0.06 0.66 ± 0.04 * 50
SEEA 50 0.82 ± 0.06 0.73 ± 0.03 0.60 ± 0.01 0.71 ± 0.03 * 47
100 0.74 ± 0.03 0.61 ± 0.02 0.49 ± 0.03 0.61 ± 0.02 * 54
SECH 50 0.88 ± 0.05 0.79 ± 0.02 0.65 ± 0.04 0.77 ± 0.03 * 42
100 0.79 ± 0.02 0.68 ± 0.04 0.56 ± 0.01 0.67 ± 0.02 * 50
SENB 50 0.89 ± 0.03 0.78 ± 0.05 0.70 ± 0.02 0.79 ± 0.03 * 41
100 0.81 ± 0.04 0.70 ± 0.02 0.62 ± 0.01 0.71 ± 0.02 * 47
SENH 50 0.93 ± 0.01 0.83 ± 0.06 0.74 ± 0.03 0.83 ± 0.03 * 38
100 0.86 ± 0.03 0.77 ± 0.03 0.68 ± 0.02 0.77 ± 0.03 * 42
SEAQ 50 0.95 ± 0.02 0.87 ± 0.02 0.79 ± 0.03 0.87 ± 0.02 * 35
100 0.88 ± 0.03 0.81 ± 0.02 0.75 ± 0.01 0.81 ± 0.02 * 39

SE, S. edelbergii; NH, n-hexane; AQ, aqueous; CH, chloroform; NB, n-BuOH; EA, EtOAc; CR, crude. Diclofenac sodium is the positive control. n = 3 with p ≤ 0.05 *; data were taken as mean ± SEM.