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Phylogenetic tree of DENV-4 based on whole-genome sequencing. The maximum likelihood tree was generated using a general time reversible (GTR + I + G) model with 1000 bootstrap replicates. Bootstrap values of >70 were indicated in the nodes. The tree shows global DENV strains, and the 20 DENV-4 isolates from this study are indicated by asterisks. Representative strains of each genotype were named by country of origin, strain name, year of isolation, and accession number (GenBank).
