Table 2.
Clinicopathological characteristics and laboratory findings of patients in the study cohort 1.
| Patients Positive for Each DENV Serotype (N, %) | ||||||
|---|---|---|---|---|---|---|
| Patient Characteristic | DENV-1 (n = 64, 30.1%) |
DENV-2 (n = 8, 3.8%) |
DENV-3 (n = 98, 46.2%) |
DENV-4 (n = 42, 19.8%) |
Total (n = 212, 100%) |
p Value |
| Age (years) | 8.8 (±5.1) 2 | 8.0 (±4.6) | 9.6 (±5.4) | 11.7 (±5.4) | 9.7 (±6.3) | |
| Age group (years) | ||||||
| ≤12 | 52 (32.5%) | 7 (4.4%) | 75 (46.8%) | 26 (16.3%) | 160 (100%) | 0.111 |
| >12 | 12 (23%) | 1 (2%) | 23 (44.2%) | 16 (30.8) | 52 (100%) | |
| Gender | ||||||
| Male | 30 (46.8%) | 6 (75%) | 64 (65.3%) | 20 (47.6%) | 120 (56.7%) | 0.047 |
| Female | 34 (53.2%) | 2 (25%) | 34 (34.7%) | 22 (52.4%) | 92 (43.3%) | |
| Signs and Symptoms | ||||||
| Rash | 3 | 0 | 8 | 3 | 14 | 0.717 |
| Hess test | 62 | 7 | 94 | 38 | 201 | 0.038 |
| Coffee ground vomiting | 4 | 1 | 13 | 1 | 19 | 0.161 |
| Muscle pain | 6 | 1 | 19 | 12 | 38 | 0.081 |
| Joint pain | 6 | 1 | 17 | 10 | 34 | 0.241 |
| Abdominal pain | 21 | 2 | 31 | 15 | 69 | 0.932 |
| Hepatomegaly | 41 | 5 | 39 | 20 | 105 | 0.027 |
| Splenomegaly | 0 | 0 | 1 | 1 | 2 | 0.632 |
| Drowsiness | 17 | 2 | 31 | 8 | 58 | 0.493 |
| Thrombocytopenia. (<150,000/μL platelets) |
26 | 2 | 32 | 20 | 80 | 0.308 |
| Epistaxis | 11 | 2 | 19 | 5 | 37 | 0.689 |
| Melena | 0 | 0 | 7 | 1 | 8 | 0.106 |
| Symptoms 3 | ||||||
| Without warning signs | 27 (42.2%) | 2 (25%) | 27 (27.5%) | 18 (42.8%) | 74 (34.9%) | |
| With warning signs | 32 (50%) | 6 (75%) | 62 (63.3%) | 19 (45.2%) | 119 (56.1%) | 0.284 |
| Severe dengue | 5 (7.8%) | 0 | 9 (9.2%) | 5 (12%) | 19 (9%) | |
| Anti-DENV IgM 4 | ||||||
| Negative | 24 (37.5%) | 3 (37.5%) | 43 (43.8%) | 12 (28.6%) | 82 (38.7%) | 0.397 |
| Positive | 40 (62.5%) | 5 (62.5%) | 55 (56.2%) | 30 (71.4%) | 130 (61.3%) | |
| Type of infection 5 | ||||||
| Primary | 31 (48.4%) | 1 (12.5%) | 50 (51%) | 5 (11.9%) | 87 (41%) | <0.001 |
| Secondary | 33 (51.6%) | 7 (87.5%) | 48 (49%) | 37 (88.1%) | 125 (59%) | |
1 Patients was confirmed positive by virus isolation, 2 Mean ± standard deviation, 3 WHO classification system, 4 as determined by capture ELISA, 5 as determined by in-house dengue IgG indirect ELISA, underline indicates statistically significant values (p value < 0.05).