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. 2021 Jun 21;11(6):408. doi: 10.3390/metabo11060408

Table 5.

The summary of date palm and its constituents improving female fertility parameters.

Date and Date Products Subjects Target Material and Method Active Component Result References
Date fruit 154 Nulliparous women The onset of labour and the need for induction Date consumer (77) and Date control group (77)
Intake (7 dates/day)
No significant difference in the onset of spontaneous labour.
Date consumption reduces the need for labour augmentation but does not expedite the onset of labour
[90]
Date fruit Females Labour parameter and delivery outcomes Date fruit group: 69 women for 4 weeks per day before
labour
Non-date fruit group: 45
Intake (6 dates/day for 4 weeks)
In the date fruit group, cervical dilation was significantly increased, there was a higher rate of spontaneous labour and the latent phase of the first stage of labour was shorter
28% of women in this group required the use of protein or oxytocin compared with 43% in the non-date fruit group
[50]
Date fruit Nulliparous women (18–35 years) who were in their 37–38th week of pregnancy Duration of labour Control group
Date consuming group (70–76 g dates daily for from the 37th week of pregnancy)
Tannins There was no significant difference between the average length of the active phase of labour in the two groups [92]
Date fruit Pregnant women Onset and progression of labour 89 participants
Control group: (31 women)
Date consuming group: 26 women (7 dates/day)
Dates + water consuming group: 32 women
(7 dates + 250 mL)
Significant positive impact on maternal outcomes on both the first and third stage of labour and fetal well-being factors
No significant difference between the date fruit consumer and their counterparts regarding cervical dilation, the regularity of uterine contraction, and maternal progression factors
[64]
Date fruit Pregnant women Postpartum Haemorrhage Group 1 (50 g oral deglet Noor dates
Group 2 (10 units of Intramuscular oxytocin)
Serotonin In the whole three hours after delivery, the blood loss means in date group was significantly less than the oxytocin group [58]
Date fruit Pregnant women Bleeding, length of labour, type of labour Total of 60
Treated Group (30) consumed 7–9 dates per day since 37th-week gestation
Control group (30)
The result of the study about the length of labour showed that there was an effect of data consumption on the length of labour with a value of p = 0.000 [61]
Date fruit Pregnant women Preeclampsia 40 Pregnant women were randomly assigned to
Control group (10)
Intervention group (30)
Intake (7 dates/day for a week)
Daily consumption of 7 Ajwa date
Has a remarkable potential to decrease MAP and ROT in pregnant women at risk of developing preeclampsia and thus prevent from preeclampsia
[94]
DPP Female reproductive study Reproductive System Intake (100 and 200 mg/kg) Flavonoid, Alkaloid, and Estradiol The use of DPP suspension during gestation and lactation increase oogenesis significantly [85]
DPP Adult female Albino rats exposed to lead acetate Ovarian function and fertility Total = 404 (4 groups)
Control Group (orally 1 mL distilled water)
T1 was given orally 150 mg/kg BW. DPP (0.5 mL)
T2 was given orally 10 mg/kg BW. Lead acetate 1 mL
T3 was given oral administration of both DPP 150 mg/kg BW and 10 mg/kg BW. lead acetate
All animals were treated via gavages needles for 6 weeks
Oral administration of DPP with a protective dose of 150 mg/kg BW lead to rebalancing the harmful effect of lead acetate in female rats [97]
Date palm syrup Nulliparous Women Labour pain Total = 80
Control Group: Water
Palm Syrup Group: Consumed pulp-free syrup added in 150 mL water
Date palm syrup significantly reduces labour pain.
Findings showed that starting impact occurred late in palm syrup usage, but it has a long relief effect
[93]
Probiotic fermented milk, Sukkary date fruit extract, and their mixture Mature late pregnant Najdi ewes Neonatal traits
Hematological Parameters
Total = 20
Group 1 (control) Group 2 (50 mL date extract every other day for the last 8th week of pregnancy
Group 3 (50 mL of probiotic fermented cow’s milk for the same period
Group 4 (50 mL of the mixture
Date extract: Fermented milk, 1:1)
Mean litter weight increased significantly in ewes given dates alone (85% more kg than control)
Fermented milk or mixture with dates did not significantly increase the litter weight.
Fermented milk alone did not show alteration in litter birth weight
[88]
Barley and date fruit (Anti hypercholesteremia Impact) Female Wistar Albino Rats Ovarian function and infertility Eight Groups (n = 12)
Control (C) Barley Group
(B): Diet containing 10% barley grains
Date Palm fruit group (D):
A diet containing 10% fruit
Barley and date group (BD)
High cholesterol diet group (H)
High cholesterol and barley grains (HB)
High cholesterol and date palm fruit group (HD)
High cholesterol and both barley and date palm fruit (HBD)
Phytomicro
nutrients polyphenols, Beta-glucan, and trace elements
Concomitant supplementation of barley and date fruit to the hypercholesterolemic group revealed marked improvement of ovarian structure and function [77]

DPP, date palm pollen; mg, milligram; kg, kilogram; BW, body weight; ROT, Roll-over-Test; MAP, mean arterial pressure.