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VIP-modulated proteins in the SF-AC co-cultures secretome. (a) Average SILAC ratios (n = 4) that represent the relative protein abundance in Fn-fs+VIP versus Fn-fs treated SF-AC co-cultures at the same time point (48 h). Ratios are presented as the media of the replicates forward and reverse for each patient. (b) Functional protein association networks and biological processes where the proteins downregulated by VIP are involved, according to the STRING database.
