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Stability of DSF-loaded nanoparticles in plasma. (A) Turbidity changes of N-NPs, TAT-NPs and PGlu-PEG/TAT-NPs pretreated with PBS containing 50% rat plasma of pH 7.4 and pH 6.5 (n = 3). (B) Supposed schematic illustration of the interaction between serum protein and DSF-loaded nanoparticles. N-NPs, DSF-loaded naked nanoparticles; TAT-NPs, DSF-loaded cationic nanoparticles; PGlu-PEG/TAT-NPs, DSF-loaded shell/core composite nanoparticles.
