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PAG increases expression level of ZO-1 at translation level. (A) Dose-dependent and time-dependent alterations of ZO-1 at the mRNA level in Caco-2 monolayers treated with 400 μg/mL PAG; (B) PAG 400 μg/mL exposure time-dependently induces phosphorylation of the translation repressor 4E-BP1 and ERK1/2 in Caco-2 monolayers. Values are presented as mean ± standard deviation (Student t-test was applied for statistical analysis, * p < 0.05, ** p < 0.01, *** p < 0.001).
