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Immunosuppressive activities of isolated compounds 1–8.
| Compound | Cytotoxicity a IC50 (μM) b |
ConA-Induced T-Cell Proliferation | LPS-Induced B-Cell Proliferation |
|---|---|---|---|
| IC50 (μM) b | IC50 (μM) b | ||
| 5 | 47 | 34 | 117 |
| 1–4, 6–8 | - | - | - |
| CsA c | 11 | 4 | 25 |
a Cell viability on murine splenocytes was tested by using CCK-8 method. b Data are presented as mean ± SD (n = 3) in μM. c Positive control.
