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Biochemical and histological changes were analyzed in golden hamsters treated with UA or UA-NLC. Seric levels of AST (A) and ALT (B); histological sections of the liver from Mesocricetus auratus treated with NLC (C) or UA-NLC at 1.25 or 5.0 mg/kg (D,E, respectively) were monitored; UA at 1.25 and 5.0 mg/kg (F,G, respectively); 5.0 mg/kg of AmB (H), and control animals untreated—CTL—(I). Hematoxylin-Eosin. 100× magnification. * p < 0.05 indicates statistical significance.
