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. 2021 Jun 19;13(6):908. doi: 10.3390/pharmaceutics13060908

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Photomicrographs of histological sections of the white pulp (WP) and red pulp (RP) areas of the spleen from golden hamsters. Infected control (A); Infected and treated with empty NLC (B); Infected and treated with 1.25 and 5.0 mg/kg UA loaded in NLC (C,D, respectively), Infected and treated with 1.25 and 5.0 mg/kg of UA (E,F, respectively) or AmB (G). Spleen histological section from healthy animals is shown in image H. Insets show in detail amastigotes forms (*) and polymorphonuclear cells (arrows) of the spleen histological sections. Magnification of 100×; scale bars: 20 μm (A–H).