Table 2.

List of genes/proteins involved in vascular calcification and how they are regulated by NRs.

Gene/Protein Involved in Vascular Calcification	NRs with Inducing Effect	NRs with Reducing Effect
TNAP/ALP	SXR/PXR [65,69,70]	PgR [105] PPARγ [108]
	ER [89] AR [95,97] LXR [120]	FXR [126]
	MR [137]	RAR [154]
BMP2	SXR/PXR [65,69] ER [84]	ER [82]
	MR [137] ERRγ [155]	PPARγ [114]
Runx-2	ERRγ [155]	PPARγ [108,114]
		FXR [127] RAR [150]
Osteocalcin	ER [89]	PPARγ [108]
MGP	SXR/PXR [67,70] ER [82]	ER [85]
	PPARγ [116] RAR [154]
OPN	SXR/PXR [67,70]	ER [85]
	ERRγ [155]	LXR [120]
OPG	SXR/PXR [67,70]	ER [90,91]
	ER [75]