Skip to main content
. 2021 Jun 18;13(12):3052. doi: 10.3390/cancers13123052

Figure 7.

Figure 7

Impact of F3 peptide-targeted liposomal C6-ceramide in the mRNA levels of PI3K/Akt pathway-associated effectors in cell lines of diverse histological origin. Representation of the relative mRNA fold-change of AKT1 and S6K1 in MDA-MB-435S, SKOV-3, MDA-MB-231, A549 and H1975 cells, following incubation with the indicated concentration of C6-ceramide encapsulated in F3 peptide-targeted liposomes ([F3]L-C6) for 4 and 24 h, at 37 °C, relative to untreated control. Data represent the mean ± SEM (n = 3; p-value was calculated using t-test, * p < 0.05).