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HBV (a) particle structures and (b) genome and ORFs. In red and green, the negative and positive strands (respectively) of HBV genome; colored boxes indicate the approximate location of the ORFs; green rectangles indicate enhancer regions and purple rectangles direct repeat regions. Abbreviations: HBV, hepatitis B virus; DR, direct repeat; Enh, enhancer; P, polymerase; S, surface; C, core; X, X protein gene.
