MPTP |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
(±)-PPHT.HCl |
(±)-2-(N-phenethyl-N-propyl)amino-5-hydroxytetralin hydrochloride |
6-OHDA |
6-hydroxydopamine |
AChE |
Acetylcholinesterase |
AR |
Adenosine receptor |
AI |
Artificial intelligence |
BDNF |
Brain-derived neurotrophic factor |
cAMP |
Cyclic adenosine monophosphate |
K
i
|
Dissociation constant |
DR |
Dopamine receptor |
GDNF |
Glial cell line-derived neurotrophic factor |
EC50
|
Half maximal effective concentration |
IC50
|
Half maximal inhibitory concentration |
H3R |
Histamine H3 receptor |
iPSC |
Induced pluripotent stem cells |
LRRK2 |
Leucine-rich repeat kinase 2 |
MAO |
Monoamine oxidase |
MAO-B |
Monoamine oxidase B |
MAPT |
Microtubule-associated protein tau |
NGF |
Nerve growth factor |
NO |
Nitric oxide |
NOR |
Nociceptin opioid receptor |
NP |
Network pharmacology |
NSCs |
Neural stem cells |
NSE |
Neuron-specific enolase |
PD |
Parkinson’s disease |
PDE4 |
Phosphodiesterase-4 |
QSAR |
Quantitative structure-activity relationship |
SI |
Selectivity index |
SAR |
Structure-activity relationship |
SVZ |
Subventricular zone |
SN |
Substantia nigra |
SVM |
Support vector machine models |
SYN |
Synpatophysin protein |
THT |
Thioflavin T |
TH |
Tyrosine hydroxylase |