Table 3.
Postvaccination serum and breast milk IgG and IgA antibodies.
| Antibodies | Day 8 ± 1 (Baseline) | Day 22 ± 2 | Day 29 ± 3 | Day 43 ± 4 | p Value * |
|---|---|---|---|---|---|
| Serum IgG (BAU/mL) | 4.62 ± 3.57 (3.2, 3.2–4.1) |
373.6 ± 237.7 (302, 197–520) |
5055.8 ± 2057.6 (4108, 3524–8000) |
3276.5 ± 1803.3 (2822, 1997–4241) |
<0.001 |
| Breast milk IgG (BAU/mL) | n.d. | 0.66 ± 0.57 (0.42, 0.32–0.76) |
10.13 ± 8.55 (6.2, 4.5–12.1) |
6.43 ± 4.33 (5.9, 3.1–7.0) |
<0.001 |
| Serum IgA (ratio) | 0.33 ± 0.37 (0.19, 0.14–0.33) |
5.55 ± 4.59 (4.53, 2.44–7.42) |
35.16 ± 17.52 (35.3, 27.7–46.0) |
9.37 ± 8.08 (7.1, 4.9–9.4) |
<0.001 |
| Breast milk IgA (ratio) | 0.55 ± 0.32 (0.49, 0.32–0.71) |
2.50 ± 2.42 (1.9, 1.1–2.7) |
7.14 ± 3.04 (8.2, 4.6–10.0) |
2.73 ± 2.13 (2.0, 1.2–3.3) |
<0.001 |
Data are presented as mean ± SD (median, IQR); study group: n = 28; n.d.—not detected; IgG breast milk lower detection limit was 0.32 BAU/mL; * Friedman’s rank test.