Table 1.
List of known PP2A subunits including additional associated names. Nervous system expression represents the highest level of PP2A subunit gene expression in a central nervous system structure. Genetic information was obtained from the UniProt protein sequence database (https://www.uniprot.org/ (accessed on 3 June 2021)).
| Subunit Family | Protein Isoform | Other Associated Name(s) | Nervous System Tissue Expression |
|---|---|---|---|
| A | Aα | PR65α | Anterior cingulate cortex |
| Aβ | PR65β | Corpus callosum | |
| B”’/Striatin | B”’ | Striatin | Corpus callosum |
| B/PR55 | Bα | B55α/PR55α | Corpus callosum |
| Bβ1 | B55β1/PR55β1 | Corpus callosum | |
| Bβ2 | B55β2/PR55β2 | Corpus callosum | |
| Bγ | B55γ/PR55γ | Caudate nucleus | |
| Bδ | B55δ/PR55δ | Dorsal/ventral thalamus | |
| B’/PR61 | Bα | B56α/PR61α | Corpus callosum |
| Bβ | B56β/PR61β | Right cerebellar hemisphere | |
| B’γ1 | B56γ1/PR61γ1 | Caudate nucleus | |
| B’γ2 | B56γ2/PR61γ2 | Caudate nucleus | |
| B’γ3 | B56γ3/PR61γ3 | Caudate nucleus | |
| B’δ | B56δ1/PR61δ | Dorsal/ventral thalamus | |
| B’ε | B56ε/PR61ε | Forebrain | |
| B”/Pr72 | B”α | PR130 | Forebrain |
| B”α | PR72 | Forebrain | |
| B”β | PR70 | Hypothalamus | |
| B”γ | G5PR | C1 segment of cervical spinal cord | |
| C | Cα | PP2Acα | Frontal cortex |
| Cβ | PP2Acβ | Dorsal/ventral thalamus |