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. 2021 Jun 21;10(6):984. doi: 10.3390/antiox10060984

Figure 4.

Figure 4

(A,B) Western immunoblotting and densitometric analysis for iNOS, COX-2, NF-κB-P65, p-NF-κBP65, IκBα and p-IκBα, t-IKKα, p-IKKα, t-JNK, p-JNK, P38, and p-P38. The values are expressed as the mean ± SEM (n = 3); columns do not share a common symbol (*, **) and differ significantly with each other (* p < 0.05 vs. normal control, ** p < 0.05 vs. DOX control).iNOS-inducible nitric oxide synthase; COX-2- cyclooxygenase-2; p-NF-κB-p65- phospho nuclear factor kappa-B-p65; t-JNK- t-Jun-amino-terminal kinase; p-JNK- p-Jun-amino-terminal kinase; p-IKKα- IκB kinase-α; P38-tumor protein; p-P38-phosphorilated p38; NOR-normal; NERO-nerolidol; DOX- doxorubicin; ND- rats administered with a single intraperitoneal dose of DOX and orally treated with NERO.