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Strategies to mimic neurodegenerative disorders based on the NVU-on-a-chip/brain-on-a-chip technology. The main models developed to mimic neurodegenerative disorders on a chip are (i) testing human/rodent cells from healthy subjects exposed to peptides/proteins (e.g., beta-amyloid, alpha-synuclein, tau-protein), (ii) testing human/rodents cells obtained from experimental or clinical subjects with neurological disorders (generated with BioRender.com [91]).
