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. 2021 Jun 26;20:60. doi: 10.1186/s12944-021-01490-0

Table 2.

Multivariable adjusted change in cSBP by quartiles of blood lipids, considered individually

Variable Change in cSBP, mmHg
(95% CI)
P value
TC, mmol/L
 Continuous, per 1 mmol/L 1.20 (0.73–1.67) < 0.001
Quartiles
 Q1: < 4.70 Ref.
 Q2: 4.70–< 5.28 0.72 (−0.57–2.00) 0.274
 Q3: 5.28–< 5.95 1.99 (0.71–3.28) 0.002
 Q4: ≥5.95 2.58 (1.28–3.88) < 0.001
TG, mmol/L
 Continuous, per 1 mmol/L 0.84 (0.49–1.19) < 0.001
Quartiles
 Q1: < 0.87 Ref.
 Q2: 0.87–< 1.24 1.51 (0.23–2.80) 0.021
 Q3: 1.24–< 1.79 2.30 (0.98–3.61) < 0.001
 Q4: ≥1.79 4.22 (2.87–5.57) < 0.001
HDL-C, mmol/L
 Continuous, per 1 mmol/L −1.43 (−2.76– − 0.10) 0.035
Quartiles
 Q1: < 1.19 Ref.
 Q2: 1.19–< 1.42 −0.74 (−2.05–0.57) 0.268
 Q3: 1.42–< 1.68 −1.00 (−2.36–0.36) 0.151
 Q4: ≥1.68 −1.60 (−3.03– − 0.17) 0.028
LDL-C, mmol/L
 Continuous, per 1 mmol/L 1.00 (0.44–1.56) < 0.001
Quartiles
 Q1: < 2.73 Ref.
 Q2: 2.73–< 3.24 1.40 (0.12–2.68) 0.032
 Q3: 3.24–< 3.78 1.35 (0.06–2.64) 0.041
 Q4: ≥3.78 2.63 (1.34–3.93) < 0.001
Non-HDL-C, mmol/L
 Continuous, per 1 mmol/L 1.38 (0.91–1.85) < 0.001
Quartiles
 Q1: < 3.22 Ref.
 Q2: 3.22–< 3.83 2.33 (1.05–3.60) < 0.001
 Q3: 3.83–< 4.49 2.14 (0.85–3.43) 0.001
 Q4: ≥4.49 3.88 (2.57–5.18) < 0.001
RLP-C, mmol/L
 Continuous, per 1 mmol/L 3.94 (2.82–5.07) < 0.001
Quartiles
 Q1: < 0.39 Ref.
 Q2: 0.39–< 0.54 1.62 (0.33–2.91) 0.014
 Q3: 0.54–< 0.73 2.19 (0.88–3.50) 0.001
 Q4: ≥0.73 4.88 (3.53–6.23) < 0.001

Model adjusted for age, sex, body mass index, estimated glomerular filtration rate, smoking status, drinking status, diabetes mellitus, antidiabetic drug use, history of myocardial infarction and history of stroke

Abbreviations: TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, non-HDL-C non-high-density lipoprotein cholesterol, RLP-C remnant lipoprotein cholesterol, cSBP central systolic blood pressure