Table 3.
Multivariable adjusted change in cSBP by quartiles of RLP-C and other lipid parameters, considered simultaneously
| Models | Change in cSBP, mmHg (95% CI) |
P value | Change in cSBP, mmHg (95% CI) |
P value | |
|---|---|---|---|---|---|
| Model I† | |||||
| RLP-C, mmol/L | LDL-C, mmol/L | ||||
| Q1: < 0.39 | Ref. | Q1: < 2.73 | Ref. | ||
| Q2: 0.39–< 0.54 | 1.43 (0.10–2.77) | 0.035 | Q2: 2.73–< 3.24 | 0.97 (−0.33–2.27) | 0.143 |
| Q3: 0.54–< 0.73 | 1.89 (0.48–3.31) | 0.009 | Q3: 3.24–< 3.78 | 0.43 (−0.92–1.79) | 0.529 |
| Q4: ≥0.73 | 4.57 (3.08–6.06) | < 0.001 | Q4: ≥3.78 | 0.93 (−0.50–2.37) | 0.202 |
| Model II† | |||||
| RLP-C, mmol/L | TC, mmol/L | ||||
| Q1: < 0.39 | Ref. | Q1: < 4.70 | Ref. | ||
| Q2: 0.39–< 0.54 | 1.47 (0.15–2.78) | 0.029 | Q2: 4.70–< 5.28 | 0.14 (−1.16–1.44) | 0.832 |
| Q3: 0.54–< 0.73 | 1.90 (0.51–3.29) | 0.007 | Q3: 5.28–< 5.95 | 0.92 (−0.42–2.26) | 0.178 |
| Q4: ≥0.73 | 4.50 (2.98–6.02) | < 0.001 | Q4: ≥5.95 | 0.66 (−0.80–2.12) | 0.374 |
| Model III† | |||||
| RLP-C, mmol/L | TG, mmol/L | ||||
| Q1: < 0.39 | Ref. | Q1: < 0.87 | Ref. | ||
| Q2: 0.39–< 0.54 | 1.22 (−0.17–2.62) | 0.087 | Q2: 0.87–< 1.24 | 0.96 (−0.41–2.32) | 0.170 |
| Q3: 0.54–< 0.73 | 1.53 (−0.07–3.13) | 0.061 | Q3: 1.24–< 1.79 | 1.02 (−0.57–2.61) | 0.209 |
| Q4: ≥0.73 | 3.91 (1.92–5.89) | < 0.001 | Q4: ≥1.79 | 1.47 (−0.50–3.43) | 0.144 |
| Model IV† | |||||
| RLP-C, mmol/L | HDL-C, mmol/L | ||||
| Q1: < 0.39 | Ref. | Q1: < 1.19 | Ref. | ||
| Q2: 0.39–< 0.54 | 1.72 (0.40–3.03) | 0.010 | Q2: 1.19–< 1.42 | 0.09 (−1.24–1.42) | 0.895 |
| Q3: 0.54–< 0.73 | 2.36 (0.99–3.73) | < 0.001 | Q3: 1.42–< 1.68 | 0.52 (−0.90–1.94) | 0.474 |
| Q4: ≥0.73 | 5.15 (3.67–6.63) | < 0.001 | Q4: ≥1.68 | 0.59 (−0.97–2.15) | 0.457 |
| Model V† | |||||
| RLP-C, mmol/L | Non-HDL-C, mmol/L | ||||
| Q1: < 0.39 | Ref. | Q1: < 3.22 | Ref. | ||
| Q2: 0.39–< 0.54 | 1.15 (−0.23–2.53) | 0.104 | Q2: 3.22–< 3.83 | 1.67 (0.31–3.03) | 0.016 |
| Q3: 0.54–< 0.73 | 1.54 (−0.00–3.08) | 0.050 | Q3: 3.83–< 4.49 | 0.79 (−0.70–2.28) | 0.300 |
| Q4: ≥0.73 | 4.10 (2.36–5.84) | < 0.001 | Q4: ≥4.49 | 1.52 (−0.16–3.20) | 0.077 |
†RLP-C and other blood lipid parameters were simultaneously entered into the multivariable regression model
Model adjusted for age, sex, body mass index, estimated glomerular filtration rate, smoking status, drinking status, diabetes mellitus, antidiabetic drug use, history of myocardial infarction and history of stroke
Abbreviations: cSBP central systolic blood pressure, RLP-C remnant lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, non-HDL-C non-high-density lipoprotein cholesterol