Figure 3.

Changes in the profile of endothelial function in the primary Sjogren syndrome. Abbreviations: VEGF: vascular endothelial growth factor; ICAM-1: intercellular adhesion molecule 1; IFN-α: interferone alpha; NF-κB: nuclear factor kappa-light-chain-enhancer of activated B cells; TNFα: tumor necrosis factor alpha; IL-6: interleukin 6; IL-8: interleukin 8; SDMA: symmetric dimethylarginine; ADMA: asymmetric dimethylarginine; ROS: reactive oxygen species; eNOS: endothelial nitric oxide synthase; ONOO-: peroxynitrite; NO: nitric oxide; FMD—flow-mediated dilation; cGMP—cyclic guanyl monophosphate; O(2)-: superoxide anion; PKG—protein kinase G; pSS: primary Sjogren syndrome, ↑: increased; ↓: decreased.