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Comparison of the optimal threshold of IHDS in different subgroups, based on the number of CD4 levels.
| Subgroup | Optimal Threshold | Sensitivity (95% CI) | Specificity (95% CI) | AUC |
|---|---|---|---|---|
| CD4 > 500 cells/mm3 | 10.360 | 0.653 (0.515–0.770) | 0.685 (0.541–0.800) | 0.720 |
| CD4 < 500 cells/mm3 | 9.989 | 0.613 (0.430–0.769) | 0.615 (0.433–0.770) | 0.651 |
| All available studies | 10.217 | 0.647 (0.541–0.741) | 0.647 (0.522–0.755) | 0.683 |
