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. 2021 Jun 16;14(6):575. doi: 10.3390/ph14060575

Table 4.

Expected organ absorbed doses of 68Ga-DOTA-MGS5 in humans based on extrapolation of the biodistribution data from mice to humans.

Target Organ Male mGy/MBq Female mGy/MBq
adrenals 8.69 × 10−3 1.15 × 10−2
brain 7.67 × 10−3 9.93 × 10−3
breasts 7.15 × 10−3 9.40 × 10−3
gallbladder wall 8.93 × 10−3 1.11 × 10−2
LLI wall 8.72 × 10−3 1.14 × 10−2
small intestine 9.05 × 10−3 1.09 × 10−2
stomach wall 1.13 × 10−2 1.47 × 10−2
ULI wall 8.90 × 10−3 1.16 × 10−2
heart wall 1.12 × 10−2 1.43 × 10−2
kidneys 2.96 × 10−2 3.79 × 10−2
liver 1.08 × 10−2 1.37 × 10−2
lungs 1.57 × 10−2 1.99 × 10−2
muscle 7.00 × 10−3 8.86 × 10−3
ovaries - 1.13 × 10−2
pancreas 9.86 × 10−3 1.24 × 10−2
red marrow 8.56 × 10−3 1.05 × 10−2
osteogenic cells 1.22 × 10−2 1.74 × 10−2
skin 6.67 × 10−3 8.76 × 10−3
spleen 8.29 × 10−3 1.05 × 10−2
testes 7.66 × 10−3 -
thymus 7.97 × 10−3 1.06 × 10−2
thyroid 7.88 × 10−3 9.91 × 10−3
urinary bladder wall 1.47 × 10−2 1.79 × 10−2
uterus - 1.13 × 10−2
total body 9.78 × 10−3 1.25 × 10−2

LLI = lower large intestine, SI = small intestine, ULI = upper large intestine.