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. 2021 Jun 26;15:326. doi: 10.1186/s13256-021-02939-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Histological sections of the liver biopsy showed a nodular infiltrate of blast cells, with ample cytoplasm, irregular nuclei and small nucleoli. There were occasional small lymphocytes intermingled with neoplastic cells. Tumour cells were diffusely positive for TdT, CD43 and CD56, as well as CD123. Only heterogeneous expression of CD4 was observed. A Nodular infiltration of the liver by blast cells. B Neoplastic cells show diffuse immunoreactivity for CD123. C Positive immunoreactivity for bcl-2. D Occasional intense positivity for p53 (less than 3%)