Table 2.

The major GO annotation terms, Fisher’s p-values and Yekutieli result (FDR under dependency) for the singular enrichment analysis (SEA) of Biological Process, Molecular Function and Cellular Component annotation terms performed on the sperm-surface proteins in the input list

Biological Process			Molecular Function			Cellular Component
Term	p-value	FDR	Term	p-value	FDR	Term	p-value	FDR
Multicellular organismal process	2.00E-27	1.40E-24	Enzyme binding	2.90E-24	2.90E-22	Membrane-bounded vesicle	5.70E-85	6.10E-83
Sexual reproduction	1.90E-25	6.60E-23	Ubiquitin protein ligase binding	8.20E-16	4.10E-14	Vesicle	5.70E-85	6.10E-83
Reproduction	1.30E-24	3.00E-22	Protein binding	6.00E-11	2.00E-09	Extracellular region part	3.80E-70	2.70E-68
Reproductive process	1.20E-22	2.10E-20	Unfolded protein binding	3.60E-09	9.00E-08	Extracellular region	3.60E-62	1.90E-60
Positive regulation of biological process	1.90E-21	2.70E-19	Protein domain specific binding	1.80E-08	3.50E-07	Cytoplasm	3.90E-32	1.60E-30
Anatomical structure development	4.70E-21	5.50E-19	Carbohydrate binding	8.40E-06	0.00014	Membrane-bounded organelle	1.60E-29	5.70E-28
Regulation of biological quality	4.20E-18	4.20E-16	Binding	0.00037	0.0037	Extracellular space	9.30E-25	2.20E-23
Positive regulation of cellular process	5.30E-18	4.70E-16	Nucleotide binding	0.00041	0.0037	Organelle	1.60E-23	3.50E-22
System development	1.10E-17	8.90E-16	Enzyme regulator activity	0.00041	0.0037	Intracellular part	8.60E-20	1.70E-18
Response to stimulus	5.10E-17	3.60E-15	Catalytic activity	0.0022	0.012	Plasma membrane	7.80E-18	1.30E-16
Cellular developmental process	1.10E-16	7.00E-15	Receptor binding	0.0024	0.012	Cytoplasmic membrane-bounded vesicle	4.80E-15	6.10E-14
Response to biotic stimulus	1.90E-13	5.60E-12				Plasma membrane part	5.00E-09	3.90E-08
						Cell part	4.80E-06	2.60E-05
						Cell	4.80E-06	2.60E-05