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(A) Hematoxylin and eosin (H&E) stain of representative pancreas from a 18-week-old HMMRΔexon8-16/Δexon8-16 mouse. (B) Immunohistochemical staining detected no RHAMM expression in the pancreas of a WT mouse and a HMMRΔexon8-16/Δexon8-16 mouse. (C-F) PCR genotyping results for HMMRΔexon8-16 (C), Cre (D), KrasG12D (E), and p53lox (F). β-actin was used as endogenous control.
