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Molecular structure of VISTA protein and its function at a cellular level.
Notes: Vista plays a role as ligand on APCs and as receptor on T cells. Modified from Tagliamento M, Bironzo P, Novello S. New emerging targets in cancer immunotherapy: the role of VISTA. ESMO Open. 2019;4:e000683.17 © 2020 The Authors. Creative Commons CC-BY-NC
Abbreviations: APC, antigen-presenting cell; TCR, T-cell receptor; MHC, Major Histocompatibility Complex.
