FIGURE 1.

Timeline and comparison of major chromosome conformation capture techniques. (a) Chronological development of chromosome conformation capture technologies colored by type of method. Major observational, mechanistic, or biological discoveries are listed above the timeline. (b) Comparison of landmark 3C‐based methods and the resolutions at which their datasets are typically analyzed. The typical resolution ranges for these technologies are historically grounded and may widen or shift with the inclusion of recent advances in methodology. Resolutions at which key features of chromatin organization typically manifest are shown on the right