Table 2.
Demographical Characteristics and Clinical Data of the Patients
| Variables | Total (n=85) | COPD (n=52) | Asthma (n=22) | ACO (n=11) |
|---|---|---|---|---|
| Demographics | ||||
| Age (y) | 67.0 [60.5; 74.0] | 68.0 [65.0; 75.8] | 58.0 [45.0; 71.0] | 63.0 [60.0; 67.0] |
| Gender(%male) | 68 (80.0) | 49 (94.2) | 8 (36.4) | 11 (100.0) |
| Weight (kg) | 66.5 [55.0; 70.0] | 65.0 [55.0; 70.0] | 67.0 [60.0; 73.0] | 72.5 [60.0; 78.0] |
| Smoking (%) | 65 (76.5) | 49 (94.2) | 2 (9.1) | 10 (90.9) |
| Smoking Index | 600.0 [2.0; 1000.0] | 800.0 [510.0;1200.0] | [0.0;0.0] | 600.0 [300.0; 800.0] |
| With respiratory diseases (%combined) | 9 (10.6) | 7 (13.5) | 1 (4.5) | 1 (9.1) |
| Education Level Illiteracy |
1 (1.2) | 1 (1.9) | 0 (0.0) | 0 (0.0) |
| Primary school | 16 (18.8) | 10 (19.2) | 5 (22.7) | 1 (9.1) |
| Junior high school | 30 (35.3) | 22 (42.3) | 5 (22.7) | 3 (27.3) |
| High school | 13 (15.3) | 8 (15.4) | 2 (9.1) | 3 (27.3) |
| University and above | 21 (24.7) | 10 (19.2) | 8 (36.4) | 3 (27.3) |
| Missing value | 4 (4.7) | 1 (1.9) | 2 (9.1) | 1 (9.1) |
| FEV1%Predicted | 59.5 [33.1, 77.8] | 57.6 [31.7, 72.9] | 86.5 [67.9, 92.7] | 45.4 [33.0, 52.2] |
| CAT | 13.0 ± 7.4 | 14.0 ± 5.1 | ||
| mMRC scale | ||||
| 0 | 8 (15.4) | 0 (0.0) | ||
| 1 | 12 (23.1) | 5 (45.5) | ||
| 2 | 16 (30.8) | 4 (36.4) | ||
| 3 | 9 (17.3) | 2 (18.2) | ||
| 4 | 7 (13.5) | 0 (0.0) | ||
| ACT | 21.0[19.0; 22.0] | |||
| Received medication education before | ||||
| Yes | 85 (100) | 52 (100) | 22 (100) | 11 (100) |
| Inhalation Type (after randomization#) | ||||
| Number of people using HAN | 29 (34.1) | 18 (34.6) | 7 (31.8) | 4 (36.4) |
| Number of people using TUR | 29 (34.1) | 19 (35.8) | 10 (47.6) | 0 (0.0) |
| Number of people using DIS | 27 (31.8) | 15 (28.3) | 5 (23.8) | 7 (63.6) |
Notes: Data are presented as mean ± SD or numbers (percentages), median [Lower quartile, Upper quartile]; #If a patient uses a DPI, the patient is included in the corresponding device group; If patients use two different DPIs, they will be randomly assigned to one of the device groups.
Abbreviations: ACO, asthma-COPD Overlap; BMI, body mass index; COPD, Chronic obstructive pulmonary disease; DPI, dry powder inhaler; HAN, HandiHaler®; TUR, Turbuhaler®; DIS, Diskus®.