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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Semin Fetal Neonatal Med. 2020 Jun 2;25(5):101123. doi: 10.1016/j.siny.2020.101123

Figure:

Figure:

Pathophysiology of Preeclampsia and Proposed Mechanisms of Actions of Preventive Agents

ASA, Aspirin; COX, cyclooxygenase; sEng, soluble endoglin; sFlt1, soluble fms-like tyrosine kinase 1; PGI2, prostaglandin I2 (prostacyclin); PlGF, placental growth factor; TXA2, thromboxane A2; VEGF, vascular endothelial growth factor