Table 4. Univariable and Multivariable Linear Regression Analysis for Analyzing Factors Associated with Quantitative US Parameters.
| Parameter | Univariable Analysis | Multivariable Analysis | |||
|---|---|---|---|---|---|
| Coefficient (95% CI) (× 10−3) | P | Coefficient (95% CI) (× 10−3) | P | ||
| AC at TAI, dB/cm/MHz | |||||
| Female gender | −2 (−49, 46) | 0.941 | |||
| Age, years | 1 (−0.1, 3) | 0.152 | |||
| BMI, kg/m2 | 13 (7, 19) | < 0.001 | 0.1 (−7. 7) | 0.944 | |
| Skin-liver capsule distance, mm | 10 (4, 15) | 0.001 | 3 (−1, 8) | 0.146 | |
| Aspartate aminotransferase, IU/L | −0.9 (−1, 1) | 0.782 | |||
| Alanine aminotransferase, IU/L | 0.5 (−0.1, 1) | 0.125 | |||
| MRI-PDFF, % | 12 (9, 14) | < 0.001 | 12 (8, 14) | < 0.001 | |
| LS at MRE, kPa | 23 (−9, 55) | 0.150 | |||
| SC at TSI | |||||
| Female gender | −42 (−78, 5) | 0.250 | |||
| Age, years | 2 (−1, 3) | 0.132 | |||
| BMI, kg/m2 | 13 (9, 18) | < 0.001 | 5 (−0.3, 10) | 0.072 | |
| Skin-liver capsule distance, mm | 8 (4, 12) | < 0.001 | 1 (−0.4, 5) | 0.858 | |
| Aspartate aminotransferase, IU/L | 0.3 (−0.2, 1) | 0.300 | |||
| Alanine aminotransferase, IU/L | 0.6 (0.1, 1) | 0.007 | 0.1 (−0.3, 0.6) | 0.924 | |
| MRI-PDFF, % | 10 (8, 12) | < 0.001 | 9 (7, 11) | < 0.001 | |
| LS at MRE, kPa | 22 (−3, 47) | 0.080 | |||
AC = attenuation coefficient, BMI = body mass index, CI = confidence interval, LS = liver stiffness, MRE = magnetic resonance elastography, MRI-PDFF = magnetic resonance imaging proton density fat fraction, SC = scatter-distribution coefficient, TAI = tissue attenuation imaging, TSI = tissue scatter-distribution imaging, US = ultrasound