Table 2.
Distribution of tumor load according to initial treatment modality
| Initial treatment | LTX (n = 66) | OP (n = 303) | Ablation (n = 84) | TACE (n = 455) | SIRT (n = 33) | SBRT (n = 18) | Systemic (n = 200) |
|---|---|---|---|---|---|---|---|
| Age (years) Mean (± SD) | 53.7 (± 9.2) | 60.5 (± 13.0) | 61.4 (± 8.6) | 61.1 (± 9.5) | 67.1 (± 7.5) | 72.6 (± 8.5) | 64.2 (± 11.0) |
| AFP (IU/ml) Mean (± SD) | 57 (± 239) | 4663 (± 37,481) | 304 (± 1842) | 1267 (± 7493) | 414 (± 870) | 213 (± 568) | 85,411 (± 443,697) |
| Largest tumor size (mm) Median (IQR 25–75) | 25 (16–35) | 50 (30–75) | 20 (14–30) | 33 (23–50) | 45 (36–72) | 40 (35–44) | 70 (40–100) |
| Tumor number Median (IQR 25–75) | 1 (1–2) | 1 (1–2) | 1 (1–2) | 2 (1–> 3) | > 3 (3–> 3) | 1 (1–2) | > 3 (3–> 3) |
| Extrahepatic spread n (%) | 0 (0) | 12 (4.0) | 0 (0) | 8 (1.8) | 2 (6.1) | 1 (5.5) | 63 (31.5) |
| CPS Median (IQR 25–75) | 8 (6–10) | 5 (5–6) | 5 (5–6) | 6 (5–8) | 5 (5–6) | 6 (5–7) | 6 (5–7) |
| BCLC Median (IQR 25–75) | B (A–C) | B (A–B) | A (A–B) | B (A–B) | A (A–B) | B (B–C) | C (B–C) |
SD standard deviation, IQR interquartile range, CPS Child–Pugh-Score, LTX liver transplantation, OP hepatic resection, Ablation ablative procedures including RFA, IRE and PEI, TACE transarterial chemoembolization, SIRT selective internal radiation therapy, SBRT stereotactic body radiotherapy, Systemic systemic therapy