Table 4.

Stage migration beyond 1^st treatment sequence. Bold font indicates the chosen initial intervention

LTX liver transplantation; OP hepatic resection; Ablation, ablative procedures including RFA, MWA, IRE and PEI; TACE transarterial chemoembolization; SIRT selective internal radiation therapy; SBRT stereotactic body radiotherapy; Systemic systemic therapy

Bold frames display subsequent treatment modalities in accordance with stage migration. Gray background highlights subsequent interventions which are indicated for the same or earlier disease stages.