Table 3.
The association of multimorbidity scores and all-cause mortality, stratified by cancer status
| Multimorbidity scores | No cancer (n = 523) | Past cancer (n = 96) | Active cancer (n = 74) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | |||||||
| HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | |
| CCI | 1.21 (1.07–1.36) | 0.002 | 1.21 (1.06–1.37) | 0.003 | 1.25 (1.05–1.48) | 0.012 | 1.27 (1.06–1.52) | 0.009 | 1.15 (0.99–1.32) | 0.054 | 1.16 (1.00–1.34) | 0.044 |
| CCI-Aa | 1.23 (1.09–1.38) | < 0.001 | 1.22 (1.08–1.37) | 0.001 | 1.23 (1.04–1.46) | 0.017 | 1.26 (1.05–1.50) | 0.012 | 1.14 (0.99–1.30) | 0.062 | 1.15 (1.00–1.33) | 0.046 |
| CIRS-G | 1.09 (1.02–1.16) | 0.007 | 1.09 (1.02–1.16) | 0.007 | 1.11 (0.99–1.23) | 0.059 | 1.11 (0.99–1.23) | 0.058 | 1.07 (0.97–1.18) | 0.168 | 1.09 (0.98–1.20) | 0.128 |
| CIRS-G severity | 1.62 (0.81–3.24) | 0.169 | 1.77 (0.87–3.61) | 0.115 | 0.95 (0.28–3.24) | 0.935 | 0.96 (0.26–3.60) | 0.956 | 1.24 (0.45–3.40) | 0.678 | 1.44 (0.52–4.04) | 0.486 |
All adjusted Cox regression analysis was adjusted for age and sex unless stated otherwise
CCI Charlson Comorbidity Index, CCI-A Charlson Comorbidity Index age-adjusted, CIRS-G Cumulative Illness Rating Scale–Geriatric, CIRS-G severity total CIRS-G score divided by the total categories endorsed in CIRS-G
aCox regression analysis only adjusted for sex