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. 2021 Jun 14;9:643781. doi: 10.3389/fcell.2021.643781

TABLE 3.

Definitions and descriptions of bone morphometric data.

Abbreviation Variable Description Standard unit
TV Total volume Volume of the entire region of interest mm3
BV Bone volume Volume of the region segmented as bone mm3
BS Bone surface area Surface of the region segmented as bone mm2
BV/TV Bone volume fraction Ratio of the segmented bone volume to the total volume of the region of interest %
BS/TV Bone surface density Ratio of the segmented bone surface to the total volume of the region of interest mm2/mm3
BS/BV Specific bone surface Ratio of the segmented bone surface to the segmented bone volume mm2/mm3
Conn.D Connectivity density A measure of the degree of connectivity of trabeculae normalized by TV 1/mm3
SMI Structure model index An indicator of the structure of trabeculae; SMI will be 0 for parallel plates and 3 for cylindrical rods -
Tb.N Trabecular number Measure of the average number of trabeculae per unit length 1/mm
Tb.Th Trabecular thickness Mean thickness of trabeculae, assessed using direct 3D methods mm
Tb.Sp Trabecular separation Mean distance between trabeculae, assessed using direct 3D methods mm
Tb.Th.SD Standard deviation of trabecular thickness Measure of the homogeneity of trabecular thickness, assessed using direct 3D methods mm
Tb.Sp.SD Standard deviation of trabecular separation Measure of the homogeneity of trabecular separation, assessed using direct 3D methods mm
DA Degree of anisotropy 1 = isotropic, >1 = anisotropic by definition; DA = length of longest divided by shortest mean intercept length vector
MIL Mean intercept length Measurements of structural anisotropy

The variables highlighted in bold are the minimal set of variables that should be reported when describing trabecular bone morphology.