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. 2021 Jun 14;8:662312. doi: 10.3389/fmed.2021.662312

Table 4.

For two specimens collected from a single patient at a single time point, next-generation sequencing was performed on deoxyribonucleic acid extracted from paired formalin-fixed, paraffin-embedded cell blocks and corresponding effusion fluid supernatants.

Specimen FFPE cell block Effusion fluid supernatant
KRAS G12D (MAF) TP53 V197E (MAF) KRAS G12D (MAF) TP53 V197E (MAF)
Pleural effusion 9.5% 9.9% 1.1% <0.1%
Peritoneal effusion (Ascites) 40.4% 42.1% 43.4% 0.8%

FFPE, formalin-fixed, paraffin-embedded; MAF, mutant allelic fraction.