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. 2021 Jun 14;11:698465. doi: 10.3389/fonc.2021.698465

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Copyright © 2021 Li, Zhai, Zhang, Zhang, Wang, Wang and Yu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of IRF4 expression with various B and T immune cell infiltration levels in LUAD by TISIDB database (n = 517). (A) IRF4 expression is significantly positively correlated with activated B Cells, memory B Cells and immature B Cells in LUAD. (B) IRF4 expression is significantly positively correlated with activated CD8+ T Cells, effective memory CD8+ T Cells and central memory CD8+ T Cells in LUAD. (C) IRF4 expression is significantly positively correlated with activated CD4+ T Cells, effective memory CD4+ T Cells and central memory CD4+ T Cells in LUAD. LUAD, Lung adenocarcinoma.