Table 3.

Univariate and multivariate analyses of OS in lung adenocarcinoma patients.

Variable	OS
	Univariate Analysis		Multivariate Analysis
	HR (95%CI)	P	HR (95%CI)	P
Age≥60 y/<60 y	1.602 (0.823-3.118)	0.165
Female/male	0.785 (0.407-1.515)	0.471
Ever/never smoking	1.093 (0.562-2.124)	0.794
Stage: IV/I-III	3.398 (1.672-6.908)	0.001	2.640 (1.264-5.514)	0.01
ECOG PS 1/0	1.254 (0.658-2.390)	0.492
IRF4-high/low	0.309 (0.152-0.630)	0.001	0.407 (0.194-0.853)	0.017

OS, overall survival; CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; HR, hazard ratio.