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Diagnostic algorithm for myasthenia gravis (MG). Having identified muscle weakness in a patient, biomarkers for myasthenia gravis should next be assessed. Detectible levels of antibodies against the acetylcholine receptor (AChR) or the muscle-specific kinase (MuSK) should be present for a firm diagnosis of MG. Seronegative patients demonstrating muscle weakness confirmed through repetitive nerve stimulation and/or single-fiber electromyography would yield a supportive diagnosis.
