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. 2021 Jun 14;12:618021. doi: 10.3389/fneur.2021.618021

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Copyright © 2021 Leopardi, Chang, Pham, Luo and Garden.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Agreement of integrated metric of evidence (IME) values for ten randomized publications. Ten research papers from the pool of included records were randomly chosen and individually assessed by three reviewers, blind to each other's scores. The interclass correlation between IME values was 0.97, demonstrating excellent reliability of the scoring system. Horizontal dotted lines indicate the threshold IME values between negligible and low (2.79), low and intermediate (4.14), and intermediate and high (5.58) levels of evidence.