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. 2021 Jun 14;11:645832. doi: 10.3389/fonc.2021.645832

Figure 5.

Figure 5

YWHAZ is highly expressed in GC and promotes GC cell proliferation. (A) qRT-PCR assays showing YWHAZ expression in GC cells normalized to GES-1. (B) YWHAZ expression in GC tissues from the GEPIA online tool (http://gepia.cancer-pku.cn/index.html). (C) Survival analysis of YWHAZ using the Kaplan–Meier plotter online tool (https://kmplot.com/analysis/). (D) Efficiencies of YWHAZ knockdown in MGC-803 and AGS cells by qRT-PCR. (E, F) CCK-8 assays showing the effects of YWHAZ on GC cell proliferation. (G, H) Colony formation assays showing the potential of YWHAZ to affect GC cell proliferation. (I) WB assays showing the effect of YWHAZ on the AKT/GSK-3β pathway. Numbers show the quantification of the relative protein amount. Significant results are presented as *P < 0.05, **P < 0.01, ***P < 0.001.