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SNHG12 promotes GC proliferation via the AKT/GSK-3β pathway. (A) IP assays showing that YWHAZ interacts with and phosphorylates AKT. (B, C) WB assays showing the effect of SNHG12 on the AKT/GSK-3β pathway. (D–F) Rescue assays validated that SNHG12 promotes GC cell proliferation by regulating YWHAZ via the AKT/GSK-3β pathway. (G) SNHG12 activates AKT pathway. Numbers show the quantification of the relative protein amount. Significant results are presented as *P < 0.05, ***P < 0.001.
