Figure 7.

SNHG12 promotes GC proliferation in vivo. (A, B) Comparison of tumor formation between the NC groups and sh-SNHG12 groups. (C) SNHG12 and Ki-67 levels between the NC groups and sh-SNHG12 groups by ISH and IHC. (D–H) Expression of YWHAZ, AKT, p-AKT, GSK-3β, and p-GSK-3β proteins in the NC and sh-SNHG12 groups by IHC. (I) Schematic illustration of the mechanism underlying SNHG12 regulation of GC proliferation. Significant results were presented as ***P < 0.001. Magnification ×200, magnification ×400, scale bar 20,000 nm.