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. 2021 Jun 14;12:665469. doi: 10.3389/fgene.2021.665469

TABLE 2.

MED and feature knockout analysis of identified brain structural and time points in ASD.

Rank Features Structure Time point MED Score Performance difference (%)
1 IPC_13pcw_F_12834 Posteroventral (inferior) parietal cortex 13 pcw 23.63 6.43
2 V1C_8yrs_M_12841 Primary visual cortex (striate cortex area V1/17) 8 years 23.24 7.79
3 STC_16pcw_M_12837 Posterior superior temporal cortex (area S1, area 3,1,2) 16 pcw 18.16 6.56
4 STR_13pcw_M_12820 Striatum 13 pcw 14.64 7.24
5 OFC_40yrs_F_12304 Orbital frontal cortex 40 years 14.64 6.43
6 MFC_8pcw_M_13058 Anterior (rostral) cingulate (medial prefrontal) cortex 8 pcw 11.91 6.7
7 DTH_12pcw_F_12960 Dorsal thalamus 12 pcw 11.52 6.56
8 AMY_8yrs_M_12981 Amygdaloid complex 8 years 10.35 6.56
9 A1C_11yrs_F_12289 Primary auditory cortex (core) 8 years 10.35 6.43
10 HIP_21yrs_F_13057 Hippocampus (hippocampal formation) 11 years 8.00 6.29
11 V1C_1yrs_F_12830 Primary visual cortex (striate cortex area V1/17) 1 year 7.61 6.97
12 ITC_11yrs_F_12289 Inferolateral temporal cortex (area TEv, area 20) 11 years 6.83 6.56
13 STC_1yrs_F_12830 Posterior superior temporal cortex (area S1, area 3,1,2) 1 year 4.49 6.15
14 A1C_16pcw_M_12837 Primary auditory cortex (core) 16 pcw 4.10 6.29
15 MD_37yrs_M_12303 Mediodorsal nucleus of thalamus 37 years 4.10 7.11
16 MFC_9pcw_M_12833 Anterior (rostal) cingulate (medial prefrontal) cortex 9 pcw 3.32 6.15
17 HIP_21pcw_M_12886 Hippocampus (hippocampal formation) 21 pcw 3.32 7.24
18 ITC_13pcw_M_12820 Inferolateral temporal cortex (area TEv, area 20) 13 pcw 2.14 6.15
19 DFC_11yrs_F_12289 Dorsolateral prefrontal cortex 11 years 2.14 6.7