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Historical overview of disease susceptibility polymorphisms identified in AS. Risk loci selected with a genome-wide significance threshold of P < 5 × 10–7 as well as secondary associations (P < 5 × 10–4 after conditioned for the primary associated SNP), in the previous studies are included. *But different SNP. §No independent support for the two loci in other East Asian cohort. AS, ankylosing spondylitis.
