TABLE 4.

Odds ratios and 95% confidence intervals for incidence of cognitive impairment in each subtype according to CVD risk levels.

		Amnestic impairment				Non-amnestic impairment
		Crude model		Adjusted model		Crude model		Adjusted model
		OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
Cardiovascular disease risk
Low risk (<10%)		Ref		Ref		Ref		Ref
Moderate risk (10 ≤ 20%)		2.66	0.93–7.62	1.88	0.64–5.48	1.83	1.13–2.96	1.66	1.01–2.73
High risk (≥20%)		4.87	1.40–16.91	3.21	0.89–11.57	2.65	1.39–5.05	2.40	1.22–4.73
Potential confounding factors
Education level	(Years)			1.00	0.88–1.14			0.91	0.85–0.98
Pulmonary disease	(n, %)			1.88	0.86–4.10			0.55	0.29–1.02
Prescribed medication	(Number)			1.02	0.83–1.24			1.16	1.05–1.27
Body mass index	(kg/m2)			1.05	0.94–1.17			0.93	0.87–0.99
Alcohol consumption habit	(n, %)			1.75	0.90–3.42			1.13	0.79–1.61
Slow gait speed	(n, %)			0.45	0.06–3.47			0.70	0.27–1.83
Depressive symptoms	(n, %)			2.03	0.85–4.86			1.12	0.64–1.95
Physical inactivity	(n, %)			0.97	0.47–2.03			1.06	0.71–1.58
Living alone	(n, %)			1.18	0.40–3.48			1.16	0.66–2.05
Employment	(n, %)			0.85	0.41–1.75			0.71	0.47–1.06
MMSE	(Score)			0.76	0.66–0.87			0.90	0.83–0.97

CI, confidence interval; CVD, cardiovascular disease; MMSE, mini-mental state examination; OR, odds ratio. The adjusted model was adjusted for all potential confounding factors assessed in the present study.