Table. Pharmacotherapy studies for hoarding.
Study | Population | Intervention | Outcome |
---|---|---|---|
Saxena, et al37 | OCD (n=32 with hoarding, n=47 without) | Paroxetine (open label, titrated to target dose of 40 mg/day), no other treatment | Both groups improved with no significant differences between groups. Hoarding symptoms improved as much as other OCD symptoms. |
Saxena and Sumner38 | Hoarding disorder (n=24) | Venlafaxine (open label, titrated to 150–300 mg/day), no other treatment | 36% decrease in UCLA Hoarding Severity Scale score, 70% classified as ‘responders’ |
Rodriguez, et al39 | Hoarding disorder (n=4), one with comorbid OCD | Methylphenidate (open label, 18–72 mg/day), usual medicines continued | 2 of the 4 subjects had a modest reduction in hoarding symptoms |
Grassi, et al40 | Hoarding disorder (n=12) | Atomoxetine (open label, flexible dose of 40–80 mg/day) | Statistically significant reduction on UCLA Hoarding Severity Scale for the group, 6 classified as ‘responders’ and 3 ‘partial responders’ |
OCD obsessive compulsive disorder