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. 2021 Jun 1;44(3):79–84. doi: 10.18773/austprescr.2021.020

Table. Pharmacotherapy studies for hoarding.

Study Population Intervention Outcome
Saxena, et al37 OCD (n=32 with hoarding, n=47 without) Paroxetine (open label, titrated to target dose of 40 mg/day), no other treatment Both groups improved with no significant differences between groups.
Hoarding symptoms improved as much as other OCD symptoms.
Saxena and Sumner38 Hoarding disorder (n=24) Venlafaxine (open label, titrated to 150–300 mg/day), no other treatment 36% decrease in UCLA Hoarding Severity Scale score, 70% classified as ‘responders’
Rodriguez, et al39 Hoarding disorder (n=4), one with comorbid OCD Methylphenidate (open label, 18–72 mg/day), usual medicines continued 2 of the 4 subjects had a modest reduction in hoarding symptoms
Grassi, et al40 Hoarding disorder (n=12) Atomoxetine (open label, flexible dose of 40–80 mg/day) Statistically significant reduction on UCLA Hoarding Severity Scale for the group, 6 classified as ‘responders’ and 3 ‘partial responders’

OCD obsessive compulsive disorder