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. 2021 Jun 14;12:692051. doi: 10.3389/fimmu.2021.692051

Table 1.

The demographics and clinical characteristic of subjects.

Characteristic NMOSD patients Normal controls
acute attack (n = 32) chronic phase (n = 29) P Value (n = 41)
Age at onset, mean (SD), years 36.2 (9.2) 37.2 (7.4) 0.660 36.0 (7.9)
Female, no. (%) 24 (75.0%) 21(72.4%) >0.999 31 (75.6%)
Duration, median (range), months 4 (1–36) 42 (11–63) <0.001 NA
Number of attacks, median (range) 1 (1–3) 3 (2–6) <0.001 NA
MRI lesion
 Spinal cord, no. (%) 12 (37.5%) 10 (34.5%) >0.999 NA
 Optic nerve, no. (%) 11 (34.4%) 11 (37.9%) 0.796 NA
 Brain, no. (%) 7 (21.8%) 5 (17.2%) 0.753 NA
 others, no. (%) 2 (6.2%) 3 (10.3%) 0.666 NA
EDSS score 4.5 (1.5-9.0) 2.0 (1.0-5.5) <0.001 NA
SBP before MRI 123.2 ± 13.1 119.5 ± 13.1 0.289 119.1 ± 14.0
DBP before MRI 77.5 ± 10.9 76.7 ± 11.1 0.782 76.9 ± 8.3
SBP after MRI 120.0 ± 13.5 117.5 ± 13.6 0.479 118.4 ± 11.3
DBP after MRI 80.2 ± 12.4 74.1 ± 13.0 0.089 74.3 ± 9.3
HR before MRI 74.1 ± 11.4 71.1 ± 10.1 0.411 72.3 ± 10.5
HR after MRI 75.2 ± 10.7 72.1 ± 10.1 0.225 73.5 ± 11.8

DBP, diastolic blood pressure; EDSS, expanded disability status scale; HR, heart rate; NA, not applicable; NMOSD, neuromyelitis optica spectrum disorders; SBP, systolic blood pressure.