Table 2.
The demographics and clinical characteristic of I-ANMOSD and II-ANMOSD.
| Characteristic | ANMOSD patients | ||
|---|---|---|---|
| Ⅰ-ANMOSD | Ⅱ-ANMOSD | P Value | |
| (n = 17) | (n = 15) | ||
| Age at onset, mean (SD), years | 35.5 (9.7) | 37.2 (7.4) | 0.633 |
| Female, no. (%) | 12 (70.6%) | 12 (80.0%) | 0.691 |
| Duration, median (range), months | 4 (1–36) | 6 (2–32) | 0.560 |
| Number of attacks, median (range) | 1 (1–3) | 2 (1–3) | 0.188 |
| MRI lesion | |||
| Spinal cord, no. (%) | 7 (41.2%) | 5 (33.3%) | 0.737 |
| Optic nerve, no. (%) | 5 (29.4%) | 6 (40.0%) | 0.712 |
| Brain, no. (%) | 4 (23.5%) | 3 (20.0%) | >0.999 |
| others, no. (%) | 1 (5.9%) | 1 (6.7%) | >0.999 |
| EDSS score | 3.5 (1.5-4.5) | 7.0 (5.0-9.0) | <0.001 |
| SBP before MRI | 125.1 ± 13.0 | 121.1 ± 13.1 | 0.390 |
| DBP before MRI | 75.7 ± 10.6 | 79.5 ± 11.4 | 0.340 |
| SBP after MRI | 121.6 ± 13.1 | 118.1 ± 14.2 | 0.480 |
| DBP after MRI | 78.2 ± 9.4 | 82.4 ± 15.0 | 0.343 |
| HR before MRI | 76.1 ± 10.4 | 71.8 ± 12.4 | 0.301 |
| HR after MRI | 77.1 ± 9.5 | 73.1 ± 11.8 | 0.291 |
DBP, diastolic blood pressure; EDSS, expanded disability status scale; HR, heart rate; I-NMOSD, neuromyelitis optica spectrum disorders (EDSS scale ≤ 4.5); II-NMOSD, neuromyelitis optica spectrum disorders (EDSS scale > 4.5); SBP, systolic blood pressure.