Table.

Summary of Key AMD-Associated Complement Genes Expressed in Specific Ocular Cell Types

	AMD1 (Control Eyes)				AMD4 (GA Eyes)
Ocular Cell Type	C3	CFB	CFH	CFI	C3	CFB	CFH	CFI
Microglia macrophage myeloid cell	45,47–50*				*	*	*	*
Fibroblast	48,49	48,49	48,49	48
Muller glia/astrocyte	49,50	49,50		45,48–50*				**
RPE			47–50 *	47,48,50*			*	*
Vascular endothelium/pericyte	50	48 *	45,48–50*	48,49

Numbers are reference numbers for published single cell or single nuclear RNASeq studies where indicated complement genes were reported in each specific ocular cell type.

^*Indicated findings from the current study.

^**The pattern of CFI mRNA distribution in INL is consistent with its expression in Müller glia cells.